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MOTS-c vial with the PureTide house label

Metabolic · Placeholder catalog data

MOTS-c

A 16-amino-acid peptide encoded within the mitochondrial 12S rRNA region, studied as a metabolic signaling molecule and modulator of AMPK-dependent pathways.

210 credits

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Available variants

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AmountSKUCreditsMSRPAvailabilityMargin estimate
10 mgPTS-MOT-1042 credits$69Ready39% estimate
40 mgPTS-MOT-4051 credits$129Ready60% estimate

Margin estimate treats 1 credit as $1 and compares estimated wholesale credit cost with placeholder MSRP. It excludes shipping, taxes, and other costs.

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Quantity breaks apply per line item and are deducted automatically at checkout.

Quantity per lineDiscountExample (10 mg unit)
10+ units5% off10 × 42 credits399 credits
25+ units10% off25 × 42 credits945 credits
50+ units15% off50 × 42 credits1,785 credits
100+ units20% off100 × 42 credits3,360 credits

Specifications

CAS
1627580-64-6
Formula
C100H162N28O25S
Molecular weight
2174.6 g/mol
Sequence
MRWQEMGYIFYPRKLR
Purity
≥99%
Appearance
White lyophilized powder
Storage
Store lyophilized at −20 °C, protected from light and moisture

Quality record

COA status

COA listed

Lot PTS-MOT-2607

Placeholder reference. Verify the active lot before ordering.

Research background

MOTS-c (Mitochondrial ORF of the Twelve S rRNA-c) is one of a small family of peptides encoded within the mitochondrial genome. Since its characterization by the Cohen group, published research has examined its role as a mitochondrial-derived signaling peptide influencing insulin sensitivity, AMPK activation, and metabolic homeostasis in preclinical models.

Studies have reported MOTS-c effects on glucose uptake in skeletal muscle, age-associated metabolic decline, and exercise-related metabolic adaptation.

The peptide is supplied as a research tool for investigation of mitochondrial signaling and the emerging field of mitochondrial-derived peptide biology.

Mechanism: Literature describes MOTS-c as an AMPK-activating peptide that traffics from mitochondria to the nucleus under metabolic stress to modulate nuclear gene expression programs.

Research use only

For research use only. Not for human or veterinary use.